Table 1 Clinical characteristics of the subjects.
No or mild OSA | Moderate to severe OSA | p-value | |
|---|---|---|---|
n = 12 | n = 11 | ||
Age (years) | 42.6 ± 7.1 | 42.1 ± 12.0 | 0.422 |
Sex (male) | 9 (75.0) | 10 (90.9) | 0.315 |
BMI (kg/m2) | 24.7 ± 2.4 | 27.7 ± 3.0 | 0.036 |
Neck circumference (cm) | 36.4 ± 3.0 | 38.2 ± 2.4 | 0.121 |
Waist circumference (cm) | 86.5 ± 7.8 | 92.4 ± 6.6 | 0.139 |
Polysomnography | |||
TST (min) | 318.4 ± 58.2 | 258.2 ± 68.1 | 0.014 |
N1% | 16.1 ± 7.4 | 28.2 ± 21.0 | 0.116 |
N2% | 45.2 ± 9.6 | 37.4 ± 10.4 | 0.085 |
N3% | 23.6 ± 11.2 | 19.8 ± 12.3 | 0.479 |
R% | 15.2 ± 5.5 | 14.6 ± 9.1 | 0.951 |
WASO (min) | 8.2 ± 3.6 | 17.3 ± 17.0 | 0.559 |
Sleep latency (min) | 7.6 ± 5.4 | 6.5 ± 8.3 | 0.090 |
REM latency (min) | 90.3 ± 36.8 | 88.3 ± 51.5 | 0.895 |
Sleep efficacy (%) | 89.6 ± 3.6 | 81.1 ± 17.3 | 0.782 |
Arousal index (/hr) | 26.6 ± 17.9 | 45.6 ± 17.6 | 0.010 |
AHI (/hr) | 6.3 ± 4.3 | 36.7 ± 18.4 | < 0.001 |
Minimum saturation (%) | 88.6 ± 3.2 | 76.0 ± 8.6 | < 0.001 |
Metabolic measures | |||
Fasting glucose (mg/dl) | 98.8 ± 11.1 | 102.2 ± 7.1 | 0.267 |
HbA1c (%) | 5.2 ± 0.4 | 5.4 ± 0.4 | 0.336 |
Insulin (µU/mL) | 5.9 ± 2.4 | 8.2 ± 4.7 | 0.356 |
HOMA-IR | 1.48 ± 0.70 | 2.07 ± 1.17 | 0.356 |
HOMA-IR > 2.5 | 1 (8.3) | 4 (36.4) | 0.131 |
FFA (µEq/L) | 495.4 ± 180.1 | 428.6 ± 248.7 | 0.310 |
Cholesterol (mg/dl) | 205.5 ± 22.3 | 207.5 ± 28.3 | 0.666 |
TG (mg/dl) | 140.9 ± 74.7 | 169.5 ± 138.3 | 0.712 |
HDL (mg/dl) | 50.7 ± 12.0 | 57.0 ± 10.3 | 0.131 |
LDL (mg/dl) | 140.4 ± 23.3 | 133.0 ± 32.9 | 0.518 |
3-Day CGM measures | |||
Average | 101.3 ± 29.5 | 111.0 ± 9.8 | 0.517 |
SD | 17.2 ± 5.3 | 17.3 ± 3.8 | 0.665 |
MAD% | 9.6 ± 5.1 | 10.6 ± 5.6 | 0.644 |
