Table 3 Summary of cytotoxic chemotherapy related complications of all high-risk UTUC patients underwent ACT strategy.
Toxic complications | Grade 1 count (%) | Grade 2 count (%) | Grade 3 count (%) | Grade 4 count (%) |
|---|---|---|---|---|
Hematological system | ||||
Leucocyte | 36 (38.3) | 9 (9.6) | 2 (2.1) | 0 |
Granulocyte | 31 (33.0) | 13 (13.8) | 2 (2.1) | 0 |
Hemoglobin | 18 (19.1) | 8 (8.5) | 2 (2.1) | 0 |
Platelet | 7 (7.4) | 4 (4.3) | 1 (1.1) | 0 |
Urinary system | ||||
Blood urea nitrogen | 19 (20.2) | 11 (11.7) | 0 | 0 |
Serum creatinine | 34 (36.2) | 6 (6.4) | 0 | 0 |
Hematuria | 26 (27.7) | 3 (3.2) | 0 | 0 |
Digestive system | ||||
Nausea/vomiting | 21 (22.3) | 12 (12.8) | 19 (20.2) | 0 |
Diarrhea | 9 (9.6) | 5 (5.3) | 0 | 0 |
Constipation | 41 (43.6) | 21 (22.3) | 1 (1.1) | 0 |
Alanine transarninase | 13 (13.8) | 8 (8.5) | 0 | 0 |
Alkaline phosphatase | 9 (9.6) | 3 (3.2) | 0 | 0 |
Bilirubin | 12 (12.8) | 2 (2.1) | 0 | 0 |
Skin/oral mucosa | ||||
Ulcer | 11 (11.7) | 6 (6.4) | 3 (3.2) | 0 |
Erythema/pruritus | 15 (16.0) | 15 (16.0) | 1 (1.1) | 0 |
Herpes | 13 (13.8) | 3 (3.2) | 2 (2.1) | 0 |
Baldness | 9 (9.6) | 5 (5.3) | 1 (1.1) | 0 |
Phlebitis | 8 (8.5) | 1 (1.1) | 1 (1.1) | 0 |
Cardiovascular system | ||||
Arrhythmia | 7 (7.4) | 2 (2.1) | 0 | 0 |
Cardiac dysfunction | 5 (5.3) | 8 (8.5) | 1 (1.1) | 0 |
Pericarditis | 1 (1.1) | 1 (1.1) | 0 | 0 |
