Figure 5 | Scientific Reports

Figure 5

From: Systemic and sustained thioredoxin analogue prevents acute kidney injury and its-associated distant organ damage in renal ischemia reperfusion injury mice

Figure 5

Effect of HSA-Trx on TNF-α-mediated pulmonary apoptosis in renal IR-mice. (A) Representative micrographs of TUNEL (green) and DAPI (blue)-double stained lung tissue are shown 36 h after renal IR with or without HSA-Trx treatment. Original magnifications: × 200. Scale bars represent 100 μm. (B) Percentage (%) of TUNEL and DAPI double-positive cells relative to total cells (DAPI-positive cells) are indicated. (C) mRNA expression of TNF-α in kidney 4 h after renal IR and plasma TNF-α level 36 h after renal IR were determined by real-time RT-PCR and ELISA, respectively. Data are expressed as means ± SD (n = 4–6).

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