Figure 6

Determination of the green fluorescence intensity inside the brain spheroids during the uptake of ultrasmall gold nanoparticles and FAM-alkyne molecules after 30 min, 6 h and 24 h of incubation under normal oxygen pressure (N-Au-Click-FAM and N-FAM) and after hypoxia, followed by incubation with either ultrasmall gold nanoparticles or FAM-alkyne molecules for 30 min (H-Au-Click-FAM and H-FAM). The fluorescence intensity was integrated and averaged from five spheroids.