Figure 1
Chemotypic distribution of cyclic and alkyl cannabinoid composition in 711 Cannabis sativa L. plants. (a) Scatter plot showing distribution of bi-axial cannabinoid chemotypes. (b) Histogram and kernel density estimates of C3-alkyl cannabinoid chemotypes. (c) Histogram and kernel density estimates of dicyclic cannabinoid chemotypes. Plants within the diversity panel were selected from the Ecofibre Global Genetic Resource Collection. Cannabinoid composition was determined from liquid chromatography-mass spectrometry (LC–MS). Dicyclic and C3-alkyl cannabinoid fractions within the total cannabinoid fraction were calculated from fresh weight (w/w) cannabinoid content. Alkyl cannabinoid values are skewed towards low C3-alkyl, while dicyclic values exhibit a tripartite chemotypic distribution. Blue diamond (CBDA) and yellow diamond (THCVA) data points represent individual plants selected for an extreme-phenotype genome-wide association study.
