Figure 2
From: NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes
Diclofenac affects cell viability in a dose-dependent way. Cell viability assay (MTS) on immortalized human cardiomyocytes upon Ketoprofen (K) (A,B) and Diclofenac (Dic) (C,D) exposure for 24–72 h. Data are mean ± SEM of three different experiments run in quintuplicate; (n = 3). (E) Images of live-imaging Cytotox assay and F) real-time graph of green fluorescence quantification obtained by Incucyte device. Data are mean ± SEM of three different experiments run in six replicates; (n = 3). Ctr versus treated, *p < 0.05; **p < 0.01; ***p < 0.001, ****p < 0.0001; Keto 100 μM versus Diclofenac 100 μM, ++p < 0.01; Keto 200 μM versus Diclofenac 200 μM, ++p < 0.01.
