Figure 5 | Scientific Reports

Figure 5

From: Cerebral dopamine neurotrophic factor (CDNF) protects against quinolinic acid-induced toxicity in in vitro and in vivo models of Huntington’s disease

Figure 5

Immunohistochemistry. Coronal sections of striatum show positive NeuN and DCX-immunoreactivity in ventral striatum of QA-lesioned animals after CDNF treatment. Scale bar: 100 μm. Scale bar for bigger magnification: 50 μm. (A) Number of NeuN- positive neurons on the left (lesioned) side versus right (non-lesioned) side. (B) Number of DCX-positive cells. Immunopositive cells were counted in the 3–5 coronal sections and expressed as mean ± SEM of the total number of cells in the same section (n = 9–23 per group). *p = 0.05, **p = 0.005, one-way ANOVA, Turkey’s post hos test. Untreated controls are set as 100. Images were taken with Pannoramic 250 digital slide scanner (3DHISTECH, Hungary).

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