Figure 4

Integration of metabolomics and transcriptomics data reveals a complex and multifaceted immune response to TB. (A) Correlation network based on gene expression values in TB cases. Highlighted genes were found to correlate with N-acetylneuraminate, quinolinate and pyridoxate with p-value < 0.05 and absolute value of R > 0.7. (B) List of pathways associated with genes found to be positively and negatively correlated with the above-mentioned 3 metabolites.