Figure 1
From: Identification of serum cytokine clusters associated with outcomes in ovarian clear cell carcinoma
Heatmap of 27 serum cytokines in EOC patients. (A) Heatmap of 27 serum cytokines in 66 CCC patients. Hierarchical clustering showed 2 cytokine signatures (C1 and C2), which classified CCC patients into 4 clusters, namely as C1hiC2hi, C1hiC2lo, C1loC2hi and C1loC2lo. (B) Heatmap of 27 serum cytokines in 73 HGSC patients. Hierarchical clustering also showed 2 cytokine signatures S1 and S2, and 4 clusters S1hiS2hi, S1hiS2lo, S1loS2hi and S1loS2lo for HGSC patients (C) Heatmap of 27 serum cytokines in 39 EMC patients. Hierarchical clustering did not show cytokine signatures, but EMC cases were categorized into two cytokine clusters, high or low overall cytokine production. R package pheatmap (version 1.0.12; https://www.rdocumentation.org/packages/pheatmap/versions/1.0.12) was used and freely available under a GPL-2 License.
