Table 1 Effect of M. bijugatus (Mb; 100 mg/kg) on cardiac output (CO), and peripheral resistance (PR) in normotensive rats and hypertensive models with l-NAME or DOCA-salt.

From: Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats

 

Normotensive rat

Hypertensive rat

Control

Mb

l-NAME

l-NAME + Mb

DOCA

DOCA + Mb

CO

0.15 ± 0.02

0.19 ± 0.01

0.23 ± 0.02

0.07 ± 0.0###

0.21 ± 0.02

0.12 ± 0.03#

PR

643 ± 21

402 ± 10***

577 ± 14

1100 ± 162###

547 ± 13

523 ± 114

  1. ***P < 0.001 vs. Control; #P < 0.05, ###P < 0.001 vs. l-NAME or DOCA. CO and PR were measured in relative units. Values are mean ± SEM of 4 experiments.
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