Table 1 Demographics and baseline characteristics.
Placebo (n = 5) | MDMA (n = 13) | Total (n = 18) | |
---|---|---|---|
Age, mean (SD), years | 53.2 (10.5) | 55.5 (7.0) | 54.9 (7.9) |
Sex, no. (%) | |||
Male | 1 (20.0) | 3 (23.1) | 4 (22.2) |
Female | 4 (80.0) | 10 (76.9) | 14 (77.8) |
Race, no. (%) | |||
White/Caucasian | 3 (60.0) | 12 (92.3) | 15 (83.3) |
Black/African-American | 1 (20.0) | 0 | 1 (5.6) |
White/Native American | 1 (20.0) | 0 | 1 (5.6) |
Other | 0 | 1 (7.7) | 1 (5.6) |
BMI (kg/m2), mean (SD) | 25.9 (3.2) | 24.8 (4.0) | 25.1 (3.8) |
Psychiatric medical history diagnosisa, no. (%) | |||
Anxiety | 3 (60.0) | 12 (92.3) | 15 (83.3) |
Major depression | 3 (60.0) | 11 (84.6) | 14 (77.8) |
Posttraumatic stress disorder | 2 (40.0) | 11 (84.6) | 13 (72.2) |
Insomnia | 2 (40.0) | 9 (69.2) | 11 (61.1) |
Prior ecstasy use (yes), no. (%) | 3 (60.0) | 7 (53.9) | 10 (55.6) |
Last use, no. (%) | |||
2–5 years | 1 (33.3) | 1 (14.3) | 2 (20.0) |
6–10 years | 1 (33.3) | 1 (14.3) | 2 (20.0) |
> 10 years | 1 (33.3) | 5 (71.4) | 6 (60.0) |
Pre-study psychotherapy type, no. (%) | |||
EMDR | 0 | 1 (7.7) | 1 (5.6) |
Group psychotherapy | 2 (40.0) | 1 (7.7) | 3 (16.7) |
Cognitive behavioral therapy | 0 | 1 (7.7) | 1 (5.6) |
Psychodynamic | 4 (80.0) | 12 (92.3) | 16 (88.9) |
Interpersonal therapy | 0 | 1 (7.7) | 1 (5.6) |
Holotropic breathwork | 1 (20.0) | 0 | 1 (5.6) |
Other | 3 (60.0) | 6 (46.2) | 9 (50.0) |
None | 0 | 0 | 0 |
Lifetime C-SSRSb, no. (%) | |||
Positive ideation | 4 (80.0) | 10 (76.9) | 14 (77.8) |
Serious ideation | 1 (20.0) | 0 | 1 (5.6) |
Positive behavior | 0 | 3 (23.1) | 3 (16.7) |
STAI-Traitc, mean (SD) | 57.4 (5.2) | 62.5 (7.3) | 61.1 (7.0) |
STAI-Stated, mean (SD) | 51.8 (5.3) | 59.5 (11.9) | 57.4 (10.9) |