Figure 3 | Scientific Reports

Figure 3

From: Contralateral spreading of substances following intratympanic nanoparticle-conjugated gentamicin injection in a rat model

Figure 3

(A) Temporal visualization of intratympanically injected fluorescent magnetic nanoparticles (F-MNPs)-conjugated gentamicin (F-MNP@GM) spreading to the contralateral tympanum. Specifically, the yellow dotted circle represents the signal intensity relevant F-MNP@GM in the contralateral tympanum at the same sequence representing the axial and coronal scans, respectively. (B) Immunostaining of cochlear hair cells for each turn of ipsilateral and contralateral cochlear hair cells after intratympanic injection of F-MNP@GM. No F-MNP@GM-related fluorescence was depicted in the contralateral apical turn of the cochlea. This figure represents rat number 1 in group 2.

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