Table 2 Particle size, zeta potential, and concentration of Fe ion of F-MNPs before and after gentamicin loading.

From: Contralateral spreading of substances following intratympanic nanoparticle-conjugated gentamicin injection in a rat model

 

Conjugation

Size (nm)

Zeta potential (mV)

Fe ion concentration (mM)

Combination

F-MNPs

NA

338.5 ± 4.7

 − 22.5 ± 0.7

363

F-MNPs 200 mL + saline 1800 mL

F-MNP@GM

Covalent bonding (by EDC/NHS coupling)

434.3 ± 15.9

 − 7.2 ± 0.5

453

F-MNPs (chemically) + gentamycin 40 mL + saline 1960 mL

  1. F-MNPs fluorescent magnetic nanoparticles, F-MNP@GM F-MNP-conjugated gentamicin, Rt right, Lt left, EDC/NHS ethyl-3-(3-(dimethylamino)-propyl)carbodiimide/N-hydroxysuccinimide, NA not available.