Figure 4 | Scientific Reports

Figure 4

From: Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor

Figure 4

The loss of epidermal MR has a major impact in the cutaneous response to topical glucocorticoids. Fold change of indicated genes (Dex/V) assessed in control (CO) and MREKO skin by RT-qPCR. (a) Down-regulated genes. (b) Up-regulated genes. Statistically significant changes between Dex/V within each genotype are denoted by asterisks and significant differences between fold changes in CO and MREKO by pound signs (*, #p < 0.05; **, ##p < 0.01; ***, ###p < 0.001).

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