Figure 3

Shared and private mutations in metachronous tumors. The mutations for selected cases (a) P2, (b) P5, (c) P9, and (d) P10 are presented in Venn diagrams that show the number of the shared mutations (blue area) and the private mutations in each sample (red area). The yellow area represents mutations shared between subset of tumors from the patient. Phylogenic trees show the mutational data and the lengths represent the number of the mutation in the respective sample. Identified driver genes are indicated in bold. Detailed information on identified gene mutations may be found in Supplementary File 1. Figure was created using R v3.6 (https://www.r-project.org/).