Figure 5 | Scientific Reports

Figure 5

From: Mucosal microbiota and gene expression are associated with long-term remission after discontinuation of adalimumab in ulcerative colitis

Figure 5

Functional characterization of 385 genes that were upregulated at week 24 in the relapse group compared with the non-relapse group (A) Enriched ontology clusters and memberships. (B) Protein–protein interaction (PPI) network and Molecular Complex Detection (MCODE) components. (C) Transcription factor analysis. Top 25 putative transcription factors based on ChEA3. Selected transcription factors were assembled from various sources and were determined by the average integrated rank. (D) Visualization of transcription factor-transcription factor local co-regulatory networks. Edges between transcription factors are defined by evidence from the ChEA3 libraries.

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