Table 3 Comparison of cell exposures.

From: Pulmonary surfactant inhibition of nanoparticle uptake by alveolar epithelial cells

Substrate

Glass coverslip

Transwell

Exposure condition to silica nanoparticles

Neat

X = 2

X = 20

Ratio

X = 20/Neat

Neat

X = 2

X = 20

Ratio

X = 20/Neat

NCI-H441

Integrated intensitya

3290

52

48

0.015

5515

90

86

0.016

Area fractionb

9.8

0.5

0.2

0.020

9.7

0.2

1

0.021

A549

Integrated intensitya

4161

43

91

0.022

12,701

1614

402

0.032

Area fractionb

15.5

0.9

0.2

0.013

15.2

4.7

1.6

0.105

  1. aFluorescence microscopy, counts of intensity divided by the total time of exposure in seconds (cps).
  2. bConfocal microscopy, %.
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