Figure 4

Dynamic bone histomorphometry can be compared across multiple animal models. (A) Mini pig buccal bone, transversal section on cryofilm, H&E staining; (B) Mini pig buccal bone, transversal section on cryofilm, vital dye labeling; (C) Timelines of vital dye labeling in mouse, rat and mini pig, time intervals are as indicated; (D) MAR calculations based on the labeling strategies presented in C, Kruskal Wallis test n.s.; (E) Mini pig alveolar bone, transversal section on cryofilm, Aniline blue staining; (F) Mini pig alveolar bone, transversal section on cryofilm, ALP staining; (G) Mini pig alveolar bone, transversal section on cryofilm, vital dye labeling detection. Scale bars as indicated. Error bars represent the standard error of the mean. ab alveolar bone.