Table 2 Comparison of T2RT histogram parameters and SIRs between untreated TAO patients and control subjects.

From: Histogram analysis of T2 mapping for detecting early involvement of extraocular muscles in patients with thyroid-associated ophthalmopathy

Parameters

Healthy controls

Normal-appearing

Involved

P

P1

P2

P3

SIR

0.97 ± 0.19

1 ± 0.14

1.08 ± 0.2

< 0.001

0.04

< 0.001

0.21

T25% (ms)

54.39 ± 8.97

53.82 ± 6.25

56.05 ± 7.04

0.02

0.06

0.17

0.85

T210% (ms)

56.91 ± 7.9

57.72 ± 5.52

59.72 ± 6.68

0.1

0.5

< 0.001

1

T225% (ms)

62.3 ± 8.02

63.32 ± 5.41

65.82 ± 7.02

< 0.001

0.03

< 0.001

0.97

T250% (ms)

68.29 ± 9.18

69.73 ± 5.94

72.77 ± 8.01

< 0.001

0.02

< 0.001

0.51

T2mean (ms)

69.46 ± 9.11

71.44 ± 5.68

74.24 ± 7.98

< 0.001

0.14

< 0.001

0.07

T275% (ms)

74.94 ± 10.52

77.07 ± 6.48

80.15 ± 9

< 0.001

0.1

< 0.001

0.15

T290% (ms)

81.07 ± 11.36

84.53 ± 7.6

87.54 ± 10.26

< 0.001

0.25

< 0.001

0.03

T295% (ms)

86.4 ± 12.21

90.39 ± 7.7

92.36 ± 11.4

< 0.001

0.99

< 0.001

0.02

SD

8.86 ± 3.22

9.77 ± 2.14

11.17 ± 3.06

< 0.001

0.008

< 0.001

0.03

Skewness

0.17 ± 0.43

0.32 ± 0.43

0.40 ± 0.39

0.002

0.97

0.001

0.03

Kurtosis

0.13 ± 0.74

0.35 ± 0.65

0.31 ± 0.79

0.06

0.59

0.003

0.11

Entropy

3.31 ± 0.14

3.38 ± 0.38

3.45 ± 0.31

< 0.001

0.33

< 0.001

0.04

Inhomogeneity

0.14 ± 0.03

0.15 ± 0.02

0.16 ± 0.03

< 0.001

0.008

< 0.001

0.01

  1. The unit of T2 is ms.
  2. P value represents the statistical difference among the three groups; P1 represents the comparison P value between involved and normal-appearing group. P2 represents the comparison P value between involved and healthy controls; P3 represents the comparison P value between normal-appearing and healthy controls.
  3. P < 0.05 is considered statistically significant. The bold vlaues represent the results with significant statistical difference.
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