Table 4 Comparison of T2RT histogram parameters for TAO patients before and after therapy.

From: Histogram analysis of T2 mapping for detecting early involvement of extraocular muscles in patients with thyroid-associated ophthalmopathy

Parameters

Involved muscles

Normal appearing muscles

Pre

Post

P

Pre

Post

P

Mean (ms)

74.19 ± 7.57

70.12 ± 7.4

< 0.001

70.79 ± 5.11

69.91 ± 5.29

0.23

T25% (ms)

55.37 ± 6.58

54.33 ± 7.26

0.04

53.13 ± 6.07

55.34 ± 5.99

0.04

T210% (ms)

59.08 ± 6.43

57.33 ± 6.16

0.001

57.02 ± 5.5

57.96 ± 5.58

0.32

T225% (ms)

65.41 ± 6.7

62.76 ± 7.23

< 0.001

62.73 ± 4.69

63.11 ± 4.94

0.61

T250% (ms)

72.8 ± 7.5

70.13 ± 6.94

< 0.001

68.98 ± 4.86

68.4 ± 5.56

0.43

T275% (ms)

82.16 ± 9.04

68.86 ± 7.57

< 0.001

76.35 ± 5.69

74.79 ± 6.3

0.03

T290% (ms)

88.06 ± 10.37

81.68 ± 9.52

< 0.001

84.26 ± 8.31

81.3 ± 7.29

0.01

T295% (ms)

92.88 ± 11.53

85.98 ± 10.66

< 0.001

89.78 ± 12

85.39 ± 7.94

0.02

SD

11.34 ± 3.07

9.22 ± 2.72

< 0.001

10.48 ± 2.7

8.66 ± 2.35

< 0.001

Skewness

0.25 ± 0.4

0.18 ± 0.39

0.16

0.38 ± 0.45

0.27 ± 0.39

0.12

Kurtosis

0.30 ± 1

− 0.01 ± 0.55

0.001

0.45 ± 0.81

− 0.06 ± 0.63

< 0.001

Entropy

3.54 ± 0.28

3.14 ± 0.38

< 0.001

3.37 ± 0.27

2.97 ± 0.36

< 0.001

Inhomogeneity

0.15 ± 0.03

0.13 ± 0.04

< 0.001

0.15 ± 0.37

0.13 ± 0.33

< 0.001

  1. ‘Pre’ represents the patients before therapy; ‘post’ represents the patients after therapy.
  2. Statistical significance is indicated by P values less than 0.05.
  3. The unit of T2 is ms.
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