Table 5 Association between UTI or pyuria without UTI (Urine WBC < 50 to ≥ 10/hpf) and clinical outcomes.

From: Pyuria, urinary tract infection and renal outcome in patients with chronic kidney disease stage 3–5

UTI

Group 0

Group 1

Group 2

No UTI

1 UTI episode

 > 1 UTI episodes

Number

3037

61

128

ESRD

Unadjusted HR

1 (reference)

1.51 (1.21–1.90)*

2.57 (2.18–3.03)*

Adjusted HR

1 (reference)

0.95 (0.75–1.21)

1.90 (1.58–2.28)*

Rapid eGFR decline

Unadjusted OR

1 (reference)

1.12 (0.82–1.54)

1.92 (1.54–2.39)*

Adjusted OR

1 (reference)

1.02 (0.71–1.46)

1.49 (1.13–1.95)*

All-cause mortality

Unadjusted HR

1 (reference)

1.74 (1.27–2.37)*

3.01 (2.45–3.69)*

Adjusted HR

1 (reference)

1.35 (0.98–1.86)

1.63 (1.29–2.05)*

Pyuria without UTI

Group 0

Group 1

Group 2

(Urine WBC < 50 to ≥ 10/hpf)

No pyuria

1–2 pyuria episode

 > 2 pyuria episodes

Number

2109

452

100

ESRD

Unadjusted HR

1 (reference)

1.61 (1.36–1.90)*

6.42 (4.88–8.45)*

Adjusted HR

1 (reference)

1.13 (0.94–1.36)

3.53 (2.63–4.75)*

Rapid eGFR decline

Unadjusted OR

1 (reference)

1.24 (0.99–1.55)

2.20 (1.46–3.31)*

Adjusted OR

1 (reference)

1.40 (1.06–1.84)*

2.01 (1.23–3.28)*

All-cause mortality

Unadjusted HR

1 (reference)

1.43 (1.12–1.83)*

2.15 (1.39–3.31)*

Adjusted HR

1 (reference)

1.20 (0.92–1.56)

1.24 (0.78–1.98)

  1. aThe model was the same as Table 4.
  2. *p < 0.05 compared with reference group.