Table 1 Clinical features of patients with AS and NC studied for scATAC-seq experiments.

From: Gene-regulatory network analysis of ankylosing spondylitis with a single-cell chromatin accessible assay

Clinical characteristic (number of samples)

AS (n = 9)

HC ( n = 12)

Age (years)*

37 ± 6

34 ± 9

Sex, Female/Male

7/2

6/6

ESR(mm/hr)*

35 ± 38

NA

CRP(mg/l)*

18 ± 21

NA

Inflammatory back pain

8/9

NA

HLA-B27 positivity

7/9

NA

Schober test (cm)*

1.5 ± 1.4

NA

Hand to floor distance (cm)*

16.5 ± 16.5

NA

Chest expansion (cm)*

2.6 ± 2.0

NA

  1. AS, ankylosing spondylitis; NC, healthy controls; PBMC, Peripheral blood mononuclear cells; NA, not applicable; ESR, Erythrocyte sedimentation rate; CRP, C-reactive protein; BASDAI, Bath AS disease activity index.
  2. *Mean ± standard deviation.