Table 5 Cox regression of mRNA expression in metastasis of breast cancer.

From: The diagnostic value of DNA repair gene in breast cancer metastasis

Variable

B

SE

Wald

P-value

OR

OR 95% CI

ER

− 0.194

0.217

0.799

0.372

0.823

0.538

1.261

HER2

− 0.338

0.228

2.204

0.138

0.713

0.456

1.114

E-Cad

− 0.163

0.363

0.203

0.653

0.849

0.417

1.729

Ki67

0.114

0.270

0.180

0.671

1.121

0.661

1.903

Molecular subtypes

Luminal A

Reference

Reference

Reference

Luminal B

0.123

0.567

0.047

0.828

1.131

0.372

3.44

Luminal HER2

0.144

0.633

0.052

0.82

1.155

0.334

3.992

HER2-enriched

− 0.016

0.698

0.001

0.982

0.984

0.251

3.863

Basal-like

− 0.338

0.228

2.204

0.138

0.713

0.456

1.114

Lymph node metastasis

0

Reference

Reference

Reference

1 ~ 3

0.149

0.335

0.198

0.656

1.161

0.602

2.238

4 ~ 9

0.702

0.307

5.208

0.022

2.017

1.104

3.685

≥ 10

1.116

0.280

15.886

< 0.001

3.053

1.763

5.286

MSH2

0.027

0.008

11.605

0.001

1.027

1.012

1.044

MLH1

− 2.723

1.019

7.146

0.008

0.066

0.009

0.484

PARP1

0.051

0.013

15.462

< 0.001

1.052

1.026

1.080

XRCC1

− 0.004

0.006

0.439

0.508

0.996

0.985

1.008

XRCC4

− 0.053

0.033

2.545

0.111

0.949

0.889

1.012

53BP1

− 0.383

0.891

0.185

0.667

0.682

0.119

3.905

ERCC1

0.033

0.031

1.106

0.293

1.033

0.972

1.099

XPA

− 0.090

0.080

1.247

0.264

0.914

0.781

1.070