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Figure 1

From: Natural bladder filling alters resting brain function at multiple spatial scales: a proof-of-concept MAPP Network Neuroimaging Study

Figure 1

MAPP-II bladder filling and neuroimaging protocol. Participants voided and then consumed approximately 350 mL of water approximately 40 min prior to entering the MRI scanner. A resting-state fMRI (rs-fMRI) scan was first acquired with fuller-bladder (rs-FB). Participants then exited the scanner and fully voided the bladder through natural urination. Participants then returned to the scanner and another resting state scan was acquired with empty bladder (rs-EB). These resting state scans were followed by structural scans: T1-weighted and diffusion tensor imaging (DTI). Tick marks along the top show time points at which volumes (either consumed or voided) were measured. Tick marks along the bottom show time points at which participants rated pain and urge to urinate (separately) on 0–10 scales.

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