Figure 2

(A) Change in urinary urge across the protocol for the “responders”. Ticks on x-axis represent average times in the protocol: when water consumption was finished (post-drink), approximately 20 min later (20 min post-drink), after the fuller bladder resting state scan (rs-FB), when the participant voided (Void), and after the empty bladder resting state scan (rs-EB). Horizontal error bars represent standard error of the mean for the indicated times, and the average time in minutes is shown for each timepoint. Vertical axis represents the participant’s self-reported urinary urge at the different time points. Vertical error bars represent the standard error of the mean. Urinary urge values shown at the post rs-FB and post rs-EB time points are the average of pre and post urinary urge values reported by participants for that scan. Paired t-test between rs-FB and rs-EB urinary urge shows a significantly greater urinary urge during the rs-FB scan (p < 0.0001). (B) Relation between bladder volume and urinary urge change. Voided volume after rs-FB was taken as a surrogate for approximate bladder volume during rs-FB. Increases in voided volume were significantly correlated with the difference in urinary urge between rs-FB and rs-EB (p = 0.0002).