Table 3 The 50% growth inhibition concentration (GI50) of compounds on various human cancer cell lines.
Entry | Compounds | Cell lines | ||||
|---|---|---|---|---|---|---|
PANC-1 (GI50) (µM) | A549 (GI50) (µM) | MCF-7 (GI50) (µM) | MiaPaCa-2 (GI50) (µM) | U87 (GI50) (µM) | ||
1 | 1 | > 1000 | > 1000 | > 1000 | > 1000 | > 1000 |
2 | 2 | > 1000 | > 1000 | > 1000 | > 1000 | > 1000 |
3 | 3 | 269.3 | > 1000 | > 1000 | > 1000 | > 1000 |
4 | 4 | 203.4 | > 1000 | 729 | > 1000 | 379.5 |
5 | 5 | 643.9 | > 1000 | > 1000 | > 1000 | > 1000 |
6 | 6 | > 1000 | > 1000 | > 1000 | > 1000 | > 1000 |
7 | 7 | 243.3 | > 1000 | > 1000 | > 1000 | > 1000 |
8 | 8 | 86.46 | > 1000 | > 1000 | > 1000 | > 1000 |
9 | 9 | 21.11 | 924.8 | 455.1 | 108 | > 1000 |
10 | 10 | 12.19 | 56.46 | 61.38 | 88.88 | 343.4 |
GSK2837808A | 11.31 | ND | ND | ND | ND | |
GNE140 | 11.93 | ND | ND | ND | ND | |
