Table 1 Distribution of general characteristics of included patients across all the groups.

From: Foveal crack sign as a predictive biomarker for development of macular hole in fellow eyes of patients with full-thickness macular holes

Characteristics

All eyes

FCS +

FCS −

p value

N = 113

Vitreous adhesion group, N = 13

Vitreous detachment group, N = 6

Vitreous adhesion group, N = 48

Vitreous detachment group, N = 46

Age, year (mean ± SD)

71 ± 7

68 ± 8

71 ± 5

71 ± 6

72 ± 8

0.412

Sex (%)

Male

33 (29)

4 (31)

1 (17)

16 (33)

12 (26)

0.788

Female

80 (71)

9 (69)

5 (83)

32 (67)

34 (74)

 

Eye (%)

Right

48 (42)

10 (77)

3 (50)

18 (38)

17 (37)

0.364

Left

65 (58)

3 (23)

3 (50)

30 (62)

29 (63)

 

BCVA, logMAR (mean ± SD)

0.08 ± 0.17

0.09 ± 0.10

0.12 ± 0.12

0.09 ± 0.19

0.06 ± 0.16

0.743

FTMH size in the fellow eye, µm (mean ± SD)

461 ± 168

471 ± 229

546 ± 189

432 ± 167

476 ± 146

0.347

Refractive error, D (mean ± SD)

0.61 ± 1.62

0.09 ± 1.51

0.27 ± 2.06

1.10 ± 1.50

0.29 ± 1.64

0.451

Follow up time, months (mean ± SD)

14 ± 10

24 ± 17

15 ± 11

13 ± 10

12 ± 7

0.003*

  1. BCVA best corrected visual acuity, logMAR logarithm of the minimal angle of resolution, FTMH full-thickness macular hole, FCS+ eyes with foveal crack sign; FCS− eyes without foveal crack sign, SD standard deviation, D diopters. Differences across the four groups were calculated using 1-way multivariate factorial ANOVA with post hoc Sidak’s test and the chi-square test according to the variables.
  2. *Statistically significant.