Table 3 Mean concentrations of plasmatic EV subtypes from subjects exposed to low-PM and high-PM levels, stratified for BMI (< or ≥ 25 kg/m2).

From: Blood-derived extracellular vesicles isolated from healthy donors exposed to air pollution modulate in vitro endothelial cells behavior

EV characterization (*103/mL PL)

Normal weight: BMI < 25 kg/m2

Overweight: BMI ≥ 25 kg/m2

P-value for interaction

(N = 3)

(N = 3)

Low-PM

High-PM

P-value

Low-PM

High-PM

P-value

Mean

95% CI

Mean

95% CI

Mean

95% CI

Mean

95% CI

CD61 + (platelets)

52

(46;59)

220

(154;315)

 < 0.0001

87

(53;142)

428

(281;650)

0.0002

0.7268

CD66 + (neutrophils)

11

(9;13)

17

(10;29)

0.1792

8

(6;11)

16

(12;21)

0.0121

0.6912

CD14 + (macrophages/monocytes)

15

(10;22)

18

(13;26)

0.3701

6

(5;7)

16

(11;24)

0.0003

0.0306

CD105 + (endothelium)

8

(7;9)

19

(13;27)

 < 0.0001

5

(3;7)

12

(8;18)

0.0003

0.7287

EpCAM + (epithelium)

8

(5;13)

18

(9;33)

0.0967

8

(5;11)

14

(12;17)

0.0001

0.6597

  1. Repeated measure analysis with poisson regression models.