Figure 4
Effect of secondary alginate hydrogel layers on the migration of cells encapsulated in the PCL-fibrin hybrid scaffold. Cells in the multiscale scaffold and PCL-fibrin hybrid scaffold were observed at 2 weeks after culture using an inverted microscope. (left) Microscope images for boundary between alginate hydrogel layer and fibrin hydrogel in the multiscale scaffold. (middle) A schematic illustration of multiscale scaffold and indication of observation site. (right) Microscope images of HUVECs migration from PCL-fibrin hybrid scaffold to outside. Scale bar = 200 μm.
