Figure 7

Immune response after subcutaneous implantation. (a) Photos showing experimental procedure for blood collection from the heart. (b) Concentrations of CXCL-1 in blood at day 7, 14, and 21 after implantation. (c) Spleen weights of C57BL/6 mice implanted with multiscale scaffolds. (d) Inflammation score. (e) Fibrosis score Data are mean ± s.d. One-way ANOVA with Tukey’s post-hoc test was used. ***P < 0.001, **P < 0.01, *P < 0.05, ns no statistical significance. Individual results are presented and the mean for each group is indicated by a straight line in all graphs.