Table 2 Mean MFM scale and QMT scores of participants before resveratrol administration.

From: Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study

 

Type of muscular dystrophy

Total (N = 11)

Duchenne (N = 5)

Becker (N = 4)

Fukuyama (N = 2)

Number (%)

Range

Mean (SD)

Number (%)

Range

Mean (SD)

Number (%)

Range

Mean (SD)

Number (%)

Range

Mean (SD)

MFM scale

5 (100)

2–63

22.2 (21.5)

4 (100)

38–85

64.5 (16.9)

2 (100)

2–10

6

11 (100)

2–85

34.6 (29.3)

QMT pinch (N)

5 (100)

0.5–2.4

11.1 (0.7)

4 (100)

0.3–4.9

3.8 (2.1)

2 (100)

0.1–0.5

0.3

11 (100)

0.1–4.9

1.9 (2.0)

QMT grip (kgf)

3 (60)

0.8–4.8

2.3 (1.8)

4 (100)

1.3–25.5

12.7 (9.5)

0 (0)

7 (64)

0.8–25.5

8.3 (8.9)

QMT scapula elevation (kgf)

4 (80)

0.9–8.6

3.3 (3.1)

4 (100)

5.3–6.8

6.0 (0.6)

2 (100)

1.4–1.4

1.4

10 (91)

0.9–8.6

4.0 (2.7)

QMT shoulder abducttion (kgf)

1 (20)

3.0 (–)

4 (100)

3.5–6.2

4.7 (1.0)

0 (0)

5 (45)

3.0–6.2

4.4 (1.1)

QMT elbow flexion (kgf)

1 (20)

1.6 (–)

4 (100)

0.6–6.2

5.1 (3.0)

1 (50)

1.1

6 (55)

0.6–6.2

3.9 (3.1)

QMT elbow extension (kgf)

1 (20)

2.8 (–)

4 (100)

3.1–9.2

5.7 (2.5)

0 (0)

5 (45)

2.8–9.2

5.1 (2.5)

QMT hip flexion (kgf)

1 (20)

5.2 (–)

4 (100)

4.3–10.1

7.7 (2.2)

0 (0)

5 (45)

4.3–10.1

7.2 (2.2)

QMT knee extension (kgf)

2 (40)

2.0–2.5

5.2 (–)

4 (100)

1.3–11.4

6.0 (3.9)

0 (0)

6 (55)

1.3–11.4

4.8 (3.6)

QMT ankle dorsiflexion (kgf)

1 (20)

5.2 (–)

4 (100)

3.2–7.9

5.4 (2.2)

1 (50)

1.4

6 (55)

1.4–7.9

4.4 (2.4)

Creatine kinase (unit/l)

5 (100)

200–9518

2522 (3518)

4 (100)

431–2807

1601 (1020)

2 (100)

840–1981

1411

11 (100)

200–9518

1985 (2512)