Figure 1
From: Unique maternal immune and functional microbial profiles during prenatal stress
Restraint stress restricts gestational weight gain. The study design is depicted in (a). While body weight gain (b) positively correlated with litter size regardless of treatment (NS: R2 = 0.27, p = 0.01; S: R2 = 0.34, p = 0.001; linear regression slope comparison, p = 0.71), linear regression y-intercepts differed across treatment groups (p = 0.04), reflecting a reduced weight gain from GD0 to GD16 with stress. This is further reflected when weight gain is normalized to litter size, revealing a (c) decreased weight gain per pup in the stressed group. Data are mean ± SEM. NS = non-stressed; n = 22, S = stressed; n = 27. *p < 0.05.
