Table 1 Demographic and laboratory parameters in the patients with different clinical diseases of chronic HBV infection.
From: Serum pentraxin 3 as a biomarker of hepatocellular carcinoma in chronic hepatitis B virus infection
Chronic hepatitis (n = 159) | Cirrhosis (n = 99) | HCC (n = 107) | P | |
|---|---|---|---|---|
Gender (male/female) | 96/63 | 61/38 | 92/15 | < 0.001 |
Age (years) | 32.30 ± 12.39 | 46.98 ± 9.18 | 49.44 ± 10.90 | < 0.001 |
HBV DNA (IU/mL, log) | 5.92 ± 1.83 | 5.34 ± 1.62 | 4.90 ± 1.50 | < 0.001 |
ALT (IU/L) | 81 (31–331) | 48 (28–84) | 54 (33–102) | 0.003 |
AST (IU/L) | 65 (29–152) | 58 (37–83) | 70 (35–150) | 0.538 |
TBIL (μmol/L) | 18.5 (11.4–84.8) | 26.1 (16.2–44.7) | 26.2 (15.2–46.7) | 0.108 |
Albumin (g/L) | 38 (34.9–41) | 30 (26.8–36.2) | 33 (29.7–39.1) | < 0.001 |
AFP (ng/mL) | 12 (6.8–26.2) | 12 (4.82–42) | 97.4 (16.8–4886) | < 0.001 |
PTX3 (ng/mL) | 3.7 (1.6–6.4) | 6.2 (3–9) | 15.6 (9.6–24.3) | < 0.001 |
