Table 1 Clinical characteristics of subjects included in the study.
Men/women | Age (years) | BMI (kg/m2) | Specific analyses | Figure | |
---|---|---|---|---|---|
Cohort 1 | |||||
Pre | 4/12 | 39.3 ± 10.9 | 53.3 ± 4.3 | Whole SC/OM | 1A-B, S1A |
Post | 4/12 | 40.3 ± 10.9 | 33.1 ± 5.0 | ||
Lean | 7/6 | 44.0 ± 17.5 | 23.0 ± 2.5 | ||
Cohort 2 | |||||
ISO | 10/20 | 44.6 ± 1.9 | 45.1 ± 1.3 | Whole SC/OM, euglycemic hyperinsulinemic clamp | 1C-D |
IRO | 10/20 | 44.9 ± 2.1 | 45.2 ± 1.3 | ||
Cohort 3 | |||||
Obese | 4/8 | 43.1 ± 10.4 | 43.7 ± 5.4 | Isolated mature SC/OM adipocytes, SVF | 2, S1B |
Lean | 5/7 | 43.5 ± 11.6 | 22.8 ± 2.1 | ||
hASCs | |||||
0/4 | 44.5 ± 6.6 | 31.2 ± 5.2 | Cultured and differentiated SC SVF | S2A, 3 | |
1/3 | 39.0 ± 13.8 | 24.0 ± 1.4 | siRNA knockdown experiments |