Table 1 Clinical characteristics of subjects included in the study.

From: COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1

 

Men/women

Age (years)

BMI (kg/m2)

Specific analyses

Figure

Cohort 1

Pre

4/12

39.3 ± 10.9

53.3 ± 4.3

Whole SC/OM

1A-B, S1A

Post

4/12

40.3 ± 10.9

33.1 ± 5.0

  

Lean

7/6

44.0 ± 17.5

23.0 ± 2.5

  

Cohort 2

ISO

10/20

44.6 ± 1.9

45.1 ± 1.3

Whole SC/OM, euglycemic hyperinsulinemic clamp

1C-D

IRO

10/20

44.9 ± 2.1

45.2 ± 1.3

  

Cohort 3

Obese

4/8

43.1 ± 10.4

43.7 ± 5.4

Isolated mature SC/OM adipocytes, SVF

2, S1B

Lean

5/7

43.5 ± 11.6

22.8 ± 2.1

  

hASCs

 

0/4

44.5 ± 6.6

31.2 ± 5.2

Cultured and differentiated SC SVF

S2A, 3

 

1/3

39.0 ± 13.8

24.0 ± 1.4

siRNA knockdown experiments

 
  1. BMI, body-mass index (kg/m2); hASCs, human adipose stromal cells; IRO, insulin resistant obese; ISO, insulin sensitive obese; OM, omental adipose tissue; Pre, before bariatric surgery; Post, one year after bariatric surgery/after profound fat loss; SC, subcutaneous adipose tissue; SVF, stromal vascular fraction.