Figure 1 | Scientific Reports

Figure 1

From: Spatial patterns of correlation between cortical amyloid and cortical thickness in a tertiary clinical population with memory deficit

Figure 1

Sample images of PET data, coregistration, and PET models. Images show (A) PET data after rigid coregistration of native PET data to MRI space; (B) initial MRI-based model of PET data derived from FreeSurfer parcels, using values from (A) as inputs, with no PVC; (C) nonlinear coregistration of native PET data to MRI space; and (D) final MRI-based PET model using input values from (C) and incorporating PVC. The correspondence between (A) and (B) was grossly adequate but insufficient for details close to the cortical ribbon. Differences are best appreciated along the margins of features (e.g., near the apex, as shown in the orange circles). The correspondence between (C) and (D) was greatly improved with the use of nonlinear coregistration and PVC (see blue circles). The colored display reflects the SUVR, with the normalized magnitude indicated by the color bar, scaled between the maximum value (which was close to SUVR = 3.0) and zero. MRI magnetic resonance imaging, PET positron emission tomography, PVC partial volume correction, SUVR standardized uptake value ratio.

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