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Figure 1

From: Fibrinolysis-resistant carbonylated fibrin detected in thrombi attached to the vascular wall of abdominal aortic aneurysms

Figure 1

Effect of CSE treatment of fibrinogen on fibrin clot lysis time and N-acetyl FDP-Lysine generation. (A) Original trace of clot lysis time of fibrin clot formed by CSE-treated fibrinogen at different concentrations. Y axis shows absorbances at 405 nm wave length and X axis shows time (hours). (B) Clot lysis time of fibrin clot formed by CSE-treated fibrinogen at different concentrations. N = 3. (C) Concentration of N-acetyl FDP-Lysine in the lysed solution of fibrin clot formed by CSE-treated fibrinogen at different concentrations. N = 3. (D) Correlation between clot lysis time and the concentration of N-acetyl FDP-Lysine in the lysed solution was analyzed by Pearson’s correlation coefficient (r = 0.75, p = 0.018). Dose-dependencies were evaluated by the Williams multiple comparison test (*p < 0.05, **p < 0.01).

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