Figure 8

Antimicrobial response and inflammation network highlighted as enriched during the comparison of control fed heifers on the restricted plane of post-insemination nutrition, when compared by pregnancy status. The network is displayed graphically as nodes (genes). The node colour indicates the expression of genes with red representing up-regulation and green indicating lower expression in the n-3 PUFA supplemented pregnant animals compared to the control group of pregnant animals The network displays nodes (genes/gene products) and edges (the biological relationship between nodes). The colour intensity of the nodes indicates the fold-change increase (red) or decrease (green) associated with a particular gene in control animals compared to n-3 PUFA supplemented. A solid line indicates a direct interaction between nodes (genes/gene products), and a dashed line indicates an indirect relationship between nodes. The shape of the node is indicative of its function. The network image was generated through the use of IPA (QIAGEN Inc., https://www.qiagenbio-informatics.com/products/ingenuity-pathway-analysis)²².