Table 4 Color differences (ΔE*) between SNADETs and the adjacent normal duodenal mucosa in WLI, LCI, and BLI-b modes.

From: Linked color imaging can improve the visibility of superficial non-ampullary duodenal epithelial tumors

 

WLI

LCI

BLI-b

WLI vs LCI, P value

WLI vs BLI-b, P value

LCI vs BLI-b, P value

(A) Color differences (ΔE*) among each modality

All lesions (n = 44), mean ± SD

8.67 ± 4.81

19.09 ± 8.33

12.92 ± 7.95

< 0.01

< 0.01

< 0.01

Lesions with MWM (n = 38)

9.22 ± 4.76

19.54 ± 8.63

13.97 ± 7.76

< 0.01

< 0.01

< 0.01

Lesions without MWM (n = 6)

5.15 ± 3.77

16.20 ± 5.91

6.30 ± 6.06

0.028

0.916

0.028

Depressed lesions (n = 15)a

8.45 ± 3.49

19.63 ± 9.66

12.02 ± 4.70

< 0.01

< 0.01

< 0.01

Non-depressed lesions (n = 29)

8.78 ± 5.43

18.81 ± 7.73

13.39 ± 9.23

< 0.01

< 0.01

< 0.01

Oral side of the major papilla (n = 19)

7.39 ± 2.89

16.96 ± 6.63

10.82 ± 4.69

< 0.01

0.013

< 0.01

Anal side of the major papilla (n = 25)

9.63 ± 5.75

20.71 ± 9.22

14.52 ± 9.51

< 0.01

0.049

0.019

 

Oral side of the major papilla (n = 19)

Anal side of the major papilla (n = 25)

P value

   

(B) Color differences (ΔE*) between lesions in oral and anal side of the major papilla

      

WLI (mean ± SD)

7.39 ± 2.89

9.63 ± 5.75

0.097

   

LCI (mean ± SD)

16.96 ± 6.63

20.71 ± 9.22

0.205

   

BLI (mean ± SD)

10.82 ± 4.69

14.52 ± 9.51

0.292

   
  1. Wilcoxon rank-sum test.
  2. WLI white light imaging, LCI linked color imaging, BLI-b blue laser imaging-bright, SD standard deviation, MWM milk white mucosa.
  3. aDepressed lesion, IIa + IIc or IIc according to the Paris endoscopic classification.
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