Table 1 Analysis of enrichment of KEGG pathways and involved genes against tobacco-flavored e-liquids.
Name | Involved genes | p-value |
|---|---|---|
Ribosome | RPL18, RPSA, RPL13, RPL35, RPL27, RPS9, RPS2, RPS5, MRPS2, RPL29, MRPL24, MRPL23, MRPL12, MRPL28, RPL18A, RPL13A, RPLP0, RPL8, RPL10, RPS10, RPL7A | 0.000 |
Glycolysis/Gluconeogenesis | PKM, GPI, LDHA, PFKL, GCK, ALDH1B1, PGM1, ALDH3B2, ALDH3B1, ENO1 | 0.003 |
Arginine and proline metabolism | PYCRL, CKMT1A, CKMT1B, SRM, ALDH1B1, GAMT, NOS3, PRODH, CKB | 0.006 |
beta-Alanine metabolism | AOC2, GAD1, AOC3, SRM, ALDH1B1, ALDH3B2, ALDH3B1 | 0.006 |
Bladder cancer | CXCL8, HBEGF, CDKN2A, FGFR3, TP53, THBS1, CDK4, MYC | 0.007 |
Phenylalanine metabolism | AOC2,AOC3, ALDH3B2, ALDH3B1, MIF | 0.012 |
Pertussis | FOS, IL6, IL23A, C3, LY96, JUN, CXCL8, PYCARD, CALML5, CD14 | 0.022 |
Galactose metabolism | HKDC1, AKR1B10, B4GALT2, PFKL, GCK, PGM1 | 0.023 |
Legionellosis | IL6, CXCL3, CXCL2, C3, PYCARD, CXCL8, CD14, HSPA8 | 0.028 |
p53 signaling pathway | CCNG2, GADD45A, STEAP3, CDKN2A, TP53, DDB2, SFN, THBS1, CDK4 | 0.030 |
Starch and sucrose metabolism | GPI, GCK, PYGL, PGM1, PYGB | 0.033 |
Salmonella infection | FOS, IL6, CXCL3, JUN, CXCL2, CXCL8, WASL, PYCARD, FLNB, CD14 | 0.039 |
Alanine, aspartate and glutamate metabolism | GFPT1, ASNS, GAD1, GLUL, ADSL, CAD | 0.042 |
Small cell lung cancer | TRAF1, PTGS2, COL4A2, LAMA5, LAMC3, RXRA, TP53, CDK4, MYC, PIK3R2 | 0.044 |
DNA replication | MCM7, LIG1, POLD2, MCM2, MCM3, MCM5 | 0.046 |
