Table 3 Go annotation of predicted targets in tobacco-flavored e-liquid.

From: Transcriptomic analysis of tobacco-flavored E-cigarette and menthol-flavored E-cigarette exposure in the human middle ear

Term

Count

%

p-value

Molecular function

GO:0003735 ~ structural constituent of ribosome

28

3.341

3.99E-06

GO:0016614 ~ oxidoreductase activity, acting on CH-OH group of donors

20

2.387

1.68E-05

GO:0005102 ~ receptor binding

102

12.172

2.01E-05

GO:0019838 ~ growth factor binding

19

2.267

2.29E-05

GO:0016616 ~ oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

18

2.148

2.50E-05

GO:0048037 ~ cofactor binding

29

3.461

6.38E-05

GO:0005198 ~ structural molecule activity

61

7.279

6.94E-05

GO:0050839 ~ cell adhesion molecule binding

40

4.773

1.91E-04

GO:0050840 ~ extracellular matrix binding

10

1.193

6.37E-04

GO:0072341 ~ modified amino acid binding

11

1.313

1.31E-03

Biological processes

GO:0055114 ~ oxidationreduction process

89

10.621

1.78E-09

GO:1901566 ~ organonitrogen compound biosynthetic process

113

13.484

2.23E-09

GO:0006364 ~ rRNA processing

38

4.535

3.08E-09

GO:0016072 ~ rRNA metabolic process

38

4.535

6.25E-09

GO:0006082 ~ organic acid metabolic process

82

9.785

9.19E-09

GO:0019752 ~ carboxylic acid metabolic process

75

8.950

3.72E-08

GO:0042594 ~ response to starvation

26

3.103

3.78E-08

GO:0043436 ~ oxoacid metabolic process

75

8.950

4.80E-08

GO:0009991 ~ response to extracellular stimulus

48

5.728

6.31E-08

GO:0006793 ~ phosphorus metabolic process

202

24.105

1.03E-07

Cellular component

GO:1903561 ~ extracellular vesicle

202

24.105

4.68E-09

GO:0043230 ~ extracellular organelle

202

24.105

4.76E-09

GO:0044421 ~ extracellular region part

258

30.788

1.18E-08

GO:0070062 ~ extracellular exosome

199

23.747

1.45E-08

GO:0031988 ~ membranebounded vesicle

238

28.401

1.58E-07

GO:0005829 ~ cytoso

214

25.537

2.67E-05

GO:0005576 ~ extracellular region

278

33.174

2.82E-05

GO:0031012 ~ extracellular matrix

48

5.728

6.23E-05

GO:0031967 ~ organelle envelope

85

10.143

1.30E-04

GO:0031975 ~ envelope

85

10.143

1.52E-04

  1. The top 10 most enriched GO terms are listed in terms for biological process, cellular component, and molecular function based on p-values.