Figure 1
From: Defective membrane repair machinery impairs survival of invasive cancer cells
Effect of collagen I fibrils on the migration of MDA-MB-231 cells. (a) Kinetics studies by phase-contrast video-microscopy of MDA-MB-231 cells seeded on a glass coverslip coated (top panel) or not (bottom panel) with collagen I. Asterisks (red, blue, green, yellow) correspond to the position of cells of interest in the course of time. Scale bar: 100 µm. (b) Tracking analysis of cells presented in (a) was performed using MTrackJ plugin from ImageJ software. Relative position of cells migrating during two hours on glass coverslip coated (left panel) or not (right panel) with collagen I was plotted. For the sake of clarity, only four and six tracks were presented in the absence or presence of collagen, respectively. Color tracks correspond to cells marked with asterisk in (a).
