Figure 1 | Scientific Reports

Figure 1

From: SHROOM3, the gene associated with chronic kidney disease, affects the podocyte structure

Figure 1

GWAS results. (a) Overviews of the GWAS for eGFR. Shown are the − log10 (P values) of the SNPs for eGFR. The genetic loci that satisfied the genome-wide significance threshold of P < 5.0 × 10−8 (red horizontal line) above the GWAS. (b) The genome-wide significant susceptibility loci in SHROOM3 region for eGFR. − log10 P values are plotted versus genomic position. The most significant SNP in each region is plotted in purple. Linkage disequilibrium (LD) based on the HapMap CEU sample is color-coded red (r2 to top SNP 0.8–1.0), orange (0.6–0.8), green (0.4–0.6), light blue (0.2–0.4) and deep blue (< 0.2).

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