Figure 1 | Scientific Reports

Figure 1

From: Acute invariant NKT cell activation triggers an immune response that drives prominent changes in iron homeostasis

Figure 1

Time course of α-GalCer-induced changes in systemic iron metabolism. Wild-type mice were injected with vehicle (indicated by the gray area across the graphs) or 100 μg/Kg body weight of α-GalCer. (A) Liver and spleen weights. (B) Total iron in liver and spleen. (C) Serum iron and transferrin saturation. (D) Hepcidin (Hamp) and ferroportin 1 (Fp1) mRNA expression. Data are presented as mean ± SEM for a minimum of n = 12 mice per time point. Statistical analysis was performed with one-way ANOVA. *(blue lines) and †(purple lines) P < 0.01, compared to mice injected with vehicle at each time point.

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