Figure 4
Iron metabolism changes induced by α-GalCer-mediated iNKT activation is independent of NK cells. Mice were injected with control isotype Ig (IgG) or with α-asialoGM1 antibodies before the administration of vehicle or 100 μg/Kg body weight of α-GalCer. (A) Liver weight 24 h post-treatment. (B) Serum iron at 6 h and 24 h post- α-GalCer treatment. (C) Hepcidin mRNA expression at 6 h and 24 h post- α-GalCer treatment. Each symbol represents one mouse with the bar indicating the mean; n = 6 per group. Statistical analysis was performed with one-way ANOVA.
