Figure 3
(a, b) Residue-wise decomposition of \(\Delta G_{\mathrm{solv}}\) for (a) Q13K and (b) Q115K mutants of mAb2 (blue, red and black colors refer to positively charged, negatively charged and neutral residues, respectively). The mutation site is indicated by the green arrow. \(d_{\mathrm{m}}\) (in Å) denotes the distance to the mutation site as illustrated in the inset (green stick representation, mutation site; cyan and orange representations, positively and negatively charged residues, respectively). Residues involved in the formation/breaking of salt-bridges upon mutation are represented by SB \(+/-\) (green if the mutation site is involved, and black otherwise). PyMOL version 1.8.2 (https://pymol.org) was used to generate protein figures.
