Figure 5
(a–c) Residue-wise decomposition of \(\Delta G_{\mathrm{solv}}\) for (a) Q13K/D73N/Q115K, (b) D32Y/S77R, and (c) Q13K/D73N/Q115K/D32Y/S77R mutants of mAb2 (blue, red and black colors refer to positively charged, negatively charged and neutral residues, respectively). The mutation sites are indicated by the green arrows. Charged residues that exhibit pronounced variations in individual single-point mutations (taken from Fig. 3 and Supplementary Fig. S2) are represented by the solid arrows labeled with respective mutations.
