Table 3 Comparison of baseline and post treatment parameters (n = 107).
Parameter | Baseline | 24 weeks | p value |
|---|---|---|---|
Bilirubin (mg/dL) | 0.78 ± 0.31 | 0.82 ± 0.37 | 0.35 |
ALT (U/L) | 94 (47–122) | 39 (31–49) | < 0.0001 |
AST(U/L) | 89 (43–114) | 37 (30–47) | < 0.0001 |
ALP (U/L) | 91 (72–142) | 88 (76–139) | 0.731 |
Albumin (g/dL) | 4.6 ± 0.4 | 4.6 ± 0.5 | 1.00 |
Total cholesterol (mg/dL) | 209.8 ± 62.4 | 185.7 ± 22.5 | 0.0003 |
LDL-C (mg/dL) | 120.9 ± 41.2 | 106.2 ± 38.2 | 0.008 |
HDL-C (mg/dL) | 38.2 ± 8.1 | 43.2 ± 9.8 | 0.0001 |
VLDL-C (mg/dL) | 50.9 ± 8.5 | 37.8 ± 9.6 | 0.007 |
Triglycerides (mg/dL) | 326.4 ± 98.5 | 168.3 ± 79.7 | < 0.0001 |
non-HDL-C (mg/dL) | 169.5 ± 44.6 | 141.7 ± 37.9 | < 0.0001 |
LDL/HDL Ratio (mg/dL) | 3.15 ± 1.1 | 2.46 ± 0.9 | < 0.0001 |
HbA1c (%) | 7.2 ± 0.65 | 6.3 ± 0.87 | 0.0001 |
LSM (kPa)† | 8.4 (7.1–9.3) | 7.5 (6.4–8.4) | 0.0261 |
IQR/M | 0.25 (0.19–0.31) | 0.24 (0.17–0.30) | 0.0067 |
CAP (dB/m)† | 335 (281–392) | 256 (212–299) | 0.0076 |
IQR/M | 0.26 (0.21–0.31) | 0.28 (0.23–0.32) | 0.0001 |
Hemoglobin (gm/dL) | 14.2 ± 2.3 | 14.1 ± 2.5 | 0.76 |
TLC (103/µl) | 6.7 ± 2.9 | 7.4 ± 3.1 | 0.09 |
Platelets (103/µl) | 194 ± 64 | 187 ± 51 | 0.38 |
Creatinine (mg/dl) | 0.92 ± 0.3 | 0.94 ± 0.3 | 0.63 |
SBP (mm Hg) | 143.5 ± 30.6 | 141.6 ± 28.7 | 0.64 |
DBP (mm Hg) | 91.4 ± 15.9 | 93.1 ± 16.9 | 0.44 |
Weight (kg) | 83.5 ± 15.1 | 80.4 ± 11.5 | 0.09 |
BMI (kg/m2) | 28.8 ± 4.2 | 27.1 ± 6.3 | 0.06 |
