Figure 4 | Scientific Reports

Figure 4

From: Saturation transfer properties of tumour xenografts derived from prostate cancer cell lines 22Rv1 and DU145

Figure 4

Segmentation masks and maps of the CEST and rNOE contributions at three frequency offsets for representative tumours with a B1 of 2 µT. The frequency offsets correspond to the resonances of the (b) amide (CEST), (c) guanidinium (CEST), and (d) aliphatic (rNOE) chemical groups. For both tumours, the active regions of the tumour show higher CEST contributions than the regions of necrosis. The CEST effects (most notably at 2 ppm) are higher in the 22Rv1 tumour. Muscle has negligible CEST effect.

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