Figure 2
From: Feasibility of continuous fever monitoring using wearable devices
Elevated temperature is clearly detectable, but only loosely correlated to changes in HR, HRV, and RR. All time points for all individuals with original (not interpolated) measurements from temperature (T), heart rate (HR), HR variability (HRV), and respiration rate (RR) sorted into those not showing fever-like days during their reported symptom window (a) and those showing fever-like days during their reported symptom windows (b). Baseline points: white. Symptom windows: color (bar in lower left, b, proportional to T, max set to threshold of digital biomarker for nighttime fever detection). Dark background points: symptom window from opposite group for comparison. Dot size proportional to RR. Insets: symptom window (dark) and baseline (white) points for that panel. NB: despite being normalized by the mean of baseline day min and max values as described for temperature (see “Methods”), HR and HRV show wide ranges, reflecting large day-to-day variance within individuals. Larger and redder spots are more apparent in the “fever-associated excursion” but not restricted to this region, reflecting the lack of strong correlation across variables. Both panels use identical axes as well as scales for color and size.
