Figure 5

Bioluminescence and fluorescence imaging of infected necropsy specimen from spinal implant infection. Following necropsy of the infected tissue bed, bioluminescence and fluorescence imaging were repeated revealing co-localization of the 1D9-680 probe with infected tissue. As shown for a representative mouse, the Vanco-800CW imaging revealed co-localization with the infected necropsy specimen, but fluorescence signal was also detected on supplemental tissue without bioluminescence.